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BNS-22 - CAS 1151668-24-4
BNS-22 - CAS 1151668-24-4
SKU:MF-0046617-01
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$116.81 USD
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$116.81 USD
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Product Details
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Bioactivity
BNS-22 is a DNA topoisomerase II (Topo II) inhibitor with IC50 values of 2.8 μM and 0.42 μM for human TopoIIα and TopoIIβ-mediated kinetoplast DNA decatenation, respectively. BNS-22 induces mitotic abnormalities and exhibits antiproliferative activity against human cancer cells.
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Target
Topoisomerase
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Related Pathways
DNA Damage/DNA Repair
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CAS Number
1151640
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Purity
0.9962
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Molecular Formula
C24H25NO5
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Molecular Weight
407.46
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SMILES
O=C1OC=2C(=C(OC)C=C(OC)C2C(=C1)CCC)C(=O)N3C=4C=CC=CC4CCC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound