Bonducellin - CAS 83162-84-9

Bonducellin has anti-inflammatory activities, it can significantly and dose-dependently inhibit the inflammatory mediators; nitric oxide (NO), and cytokines [tumor necrosis factor (TNF) -alpha and interleukin (IL) -12. Bonducellin shows weak antimalarial activity against Plasmodium falciparum with the IC50 value of 26 uM; it also shows weak antiproliferative against A2780 human ovarian cancer cell line , with the IC50 value of 10.6 uM. Bonducellin shows modulation in the MIC of EtBr by eight fold at a concentration of 62.5 mg/L and also shows significant efflux pump inhibitory activity.

Antibacterial

Microbiology/Virology

83069

C17H14O4

282.29

COc1ccc(\C=C2/COc3cc(O)ccc3C2=O)cc1

-20°C

Ice Packs

Natural Product