Bortezomib - CAS 179324-69-7

Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective. Bortezomib has antitumor activity and inhibits NF-κB, which can disrupt the cell cycle and induce apoptosis.

Apoptosis, NF-κB, Proteasome, Autophagy

Ubiquitination, NF-κB, Apoptosis, Proteases/Proteasome, Autophagy

179324-69-7

>99.99%

C19H25BN4O4

384.24

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O

-20°C

Ice Packs

Small Compound