Molfinity

Borussertib - CAS 1800070-77-2

SKU:MF-0013994-01

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Size 1 mg 5 mg 1 mL - 10 mM (in DMSO) 10 mg 25 mg 50 mg 100 mg

Product Details

Bioactivity
Borussertib is a first-in-class covalent-allosteric inhibitor of protein kinase Akt, with an IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt.
Target
Akt
Related Pathways
Cytoskeletal Signaling, PI3K/Akt/mTOR signaling
CAS Number
1799991
Purity
0.99
Molecular Formula
C36H32N6O3
Molecular Weight
596.68
SMILES
C=CC(=O)Nc1ccc2[nH]c(=O)n(C3CCN(Cc4ccc(cc4)-c4nc5cc[nH]c(=O)c5cc4-c4ccccc4)CC3)c2c1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound