BPD - CAS 213481-12-0

BPD is a COX-2 and TAK1-NF-κB inhibitor with an IC50 of 18.5 μM for COX-2. It suppresses the expression of iNOS, TNF-α, IL-6, and IL-1β at the transcriptional level. BPD possesses anti-inflammatory properties and can inhibit carrageenan-induced paw edema as well as LPS-induced septic death.

COX, NF-κB

Neuroscience, Immunology/Inflammation, NF-κB

213469

C17H10O5

294.258

O=C1OC(=O)C(C=2C=CC=3OCOC3C2)=C1C=4C=CC=CC4

-20°C

Ice Packs

Small Compound