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Molfinity
BQZ-485 - CAS 1906915-49-8
BQZ-485 - CAS 1906915-49-8
SKU:MF-0157436-01
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Product Details
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Bioactivity
BQZ-485, a potent GDI2 inhibitor, interacts with Tyr245 to disrupt the native GDI2-Rab1A interaction. This disruption impedes vesicular transport from the endoplasmic reticulum (ER) to the Golgi apparatus, triggering subsequent paraptosis events [1].
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Target
Apoptosis
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Related Pathways
Apoptosis
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CAS Number
1906858
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Molecular Formula
C32H39NO3
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Molecular Weight
485.66
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SMILES
O(CC1=CC(C)=CC(C)=C1)C=2C=C3[C@@]4(N(CCC3=CC2OCC5=CC(C)=CC(C)=C5)[C@@H](C)C[C@H](O)C4)[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound