Br-PBTC - CAS 1839519-57-1

Br-PBTC is a highly potent, 2/4 subtype-selective positive allosteric modulator of nicotinic acetylcholine receptors (nAChRs) . It specifically targets α2β2, α2β4, α4β2, α4β4, (α4β2) 2α4, and (α4β2) 2β2 subtypes of nAChRs, with EC50 values ranging from 0.1 to 0.6 μM. Br-PBTC exerts its activity by binding to the c-tail region of an α subunit.

Others, AChR

Others, Neuroscience

1839461

C14H15BrN2OS

339.25

Brc1cccc2cc(sc12)C(=O)N[C@@H]1CCCNC1

-20°C

Ice Packs

Small Compound