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Molfinity

BRAF V600E/CRAF-IN-2 - CAS 2499499-62-4

BRAF V600E/CRAF-IN-2 - CAS 2499499-62-4

SKU:MF-0140667-01

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  • Bioactivity

    BRAF V600E/CRAF-IN-2 is a potent inhibitor of BRAFV600E/CRAF with IC50 values of 0.888 and 0.229 μM, respectively.BRAF V600E/CRAF-IN-2 induces cell cycle arrest at G0/G1 phase and apoptosis in HCT-116 colon cancer cells.BRAF V600E/CRAF-IN-2 has shown research potential for cancer disease. CRAF-IN-2 has shown potential for research into cancer disease.

  • Target

    Others, Raf

  • Related Pathways

    Others, MAPK

  • CAS Number

    2499433

  • Molecular Formula

    C30H30F3N5O2

  • Molecular Weight

    549.59

  • SMILES

    C(NC1=CC(NC2=NC3=C(C=C2)C(OC)=CC=C3)=CC=C1)(=O)C=4C=C(C=C(C(F)(F)F)C4)N5CCN(CC)CC5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound