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BRAF V600E/CRAF-IN-2 - CAS 2499499-62-4
BRAF V600E/CRAF-IN-2 - CAS 2499499-62-4
SKU:MF-0140667-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
BRAF V600E/CRAF-IN-2 is a potent inhibitor of BRAFV600E/CRAF with IC50 values of 0.888 and 0.229 μM, respectively.BRAF V600E/CRAF-IN-2 induces cell cycle arrest at G0/G1 phase and apoptosis in HCT-116 colon cancer cells.BRAF V600E/CRAF-IN-2 has shown research potential for cancer disease. CRAF-IN-2 has shown potential for research into cancer disease.
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Target
Others, Raf
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Related Pathways
Others, MAPK
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CAS Number
2499433
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Molecular Formula
C30H30F3N5O2
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Molecular Weight
549.59
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SMILES
C(NC1=CC(NC2=NC3=C(C=C2)C(OC)=CC=C3)=CC=C1)(=O)C=4C=C(C=C(C(F)(F)F)C4)N5CCN(CC)CC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound