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Molfinity

Bragsin2 - CAS 342795-08-8

Bragsin2 - CAS 342795-08-8

MF-0032465-01

$51.11 USD
$51.11 USD
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Product Details

  • Bioactivity

    Bragsin2 (6-methoxy-5-nitro-2- (trifluoromethyl) chromen-4-one) is a hydration-resistant cell penetrant, selective and non-competitive inhibitor of Afr guanine nucleotide exchange factor BRAG2 that inhibits Arf GTPase activation, with an IC50 of 3 μM. Bragsin2 binds at the interface between the pleckstrin homology domain of BRAG2 and the lipid bilayer, leading BRAG2 unable to activate lipidated Arf GTPase.

  • Target

    MDM-2/p53, Ras, Others

  • Related Pathways

    Apoptosis, MAPK, Others

  • CAS Number

    342795-08-8

  • Purity

    0.9987

  • Molecular Formula

    C11H6F3NO5

  • Molecular Weight

    289.16

  • SMILES

    COc1ccc2oc(cc(=O)c2c1[N+]([O-])=O)C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound