BRD0476 - CAS 1314958-91-2

BRD0476 is a suppressor of pancreatic β-cell apoptosis. BRD0476 inhibits interferon-gamma (IFN-γ) -induced Janus kinase 2 (JAK2) and signal transducer and activation of transcription 1 (STAT1) signaling to promote β-cell survival. BRD0476 inhibits JAK-STAT signaling without suppressing the kinase activity of any JAK.

Apoptosis, Others

Others, Apoptosis

1314865

C35H38N4O8S

674.76

N(C(NC=1C2=C(C=CC1)C=CC=C2)=O)C3=C4C(C(=O)N([C@H](CO)C)C[C@@H](C)[C@H](CN(S(=O)(=O)C=5C=C6C(=CC5)OCCO6)C)O4)=CC=C3

-20°C

Ice Packs

Small Compound