BRD4/CK2-IN-1 - CAS 2756851-99-5

BRD4/CK2-IN-1 is a small molecule inhibitor targeting BRD4 and CK2, with an IC50 of 180nM for BRD4 and 230nM for CK2. It inhibits the proliferation of MDA-MB-231 and MDA-MB-468 cells, inducing apoptosis and autophagy-related cell death. It can be used in triple-negative breast cancer research.

Apoptosis, Casein Kinase, Epigenetic Reader Domain, Autophagy

Chromatin/Epigenetic, Metabolism, Autophagy, Stem Cells, Apoptosis

2756747

0.9902

C29H30ClN5O5

564.03

O=C1N=C(NC=2C=C(OC)C=C(OC)C12)C=3C=CC(OCC(=O)NC4=CC=C(C(Cl)=C4)N5CCN(C)CC5)=CC3

-20°C

Ice Packs

Small Compound