BRD4 Inhibitor-15 - CAS 2761366-60-1

BRD4 Inhibitor-15 (compound 13) is a highly potent and specific BRD4 inhibitor with an IC50 of 18 nM, inducing apoptosis in 22RV1 cells by regulating Bcl-2/Bax proteins and activating caspase-3 signaling, and down-regulating c-Myc levels, making it valuable for prostate cancer research [1].

Bcl-2 Family, Epigenetic Reader Domain, c-Myc, Caspase, Apoptosis, Others

Others, Proteases/Proteasome, Chromatin/Epigenetic, Apoptosis, Cell Cycle/Checkpoint

2761305

C22H21N3O2

359.42

C(N1C=2C(=CC=C(C2)C=3C(OCC)=CC(=O)N(C)C3)C=N1)C4=CC=CC=C4

-20°C

Ice Packs

Small Compound