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Molfinity

BRD4 Inhibitor-18 - CAS 2451219-73-9

BRD4 Inhibitor-18 - CAS 2451219-73-9

MF-0037029-01

$1,927.85 USD
$1,391.00 USD $1,927.85 USD
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Product Details

  • Bioactivity

    BRD4 Inhibitor-18 is a potent BRD4 inhibitor (IC50: 110 nM) with a hydrophobic acetylcyclopentane side chain. BRD4 Inhibitor-18 significantly reduces the proliferation of MV-4-11 cells with high BRD4 levels, inhibits G0/G1 cycle activity, and promotes apoptosis. The inhibition of G0/G1 cycle activity and apoptosis were also observed.

  • Target

    Others, Apoptosis, Epigenetic Reader Domain, c-Myc

  • Related Pathways

    Others, Chromatin/Epigenetic, Cell Cycle/Checkpoint, Apoptosis

  • CAS Number

    2451219-73-9

  • Molecular Formula

    C26H26ClN3O3S

  • Molecular Weight

    496.02

  • SMILES

    CN1C=2C=3C(C(=NC(CC(NC4CCCC4)=O)C2SC1=O)C5=CC=C(Cl)C=C5)=CC(OC)=CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound