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BRD6989 - CAS 642008-81-9
BRD6989 - CAS 642008-81-9
SKU:MF-0015878-01
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$32.42 USD
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$32.42 USD
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Product Details
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Bioactivity
BRD6989 is an analog of the natural product cortistatin A (dCA) . Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM.
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Target
Interleukin, IL Receptor, CDK
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Related Pathways
Cell Cycle/Checkpoint, Immunology/Inflammation
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CAS Number
641918
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Purity
0.9943
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Molecular Formula
C16H16N4
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Molecular Weight
264.33
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SMILES
CC1CCc2nc(N)c(C#N)c(-c3cccnc3)c2C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound