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BRD7-IN-1 - CAS 2448414-48-8
BRD7-IN-1 - CAS 2448414-48-8
SKU:MF-0034710-01
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$106.25 USD
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$106.25 USD
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Product Details
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Bioactivity
BRD7-IN-1, a modified derivative of BI7273 (BRD7/9 inhibitor), forms PROTAC VZ185 via linkage to a VHL ligand, demonstrating potent activity against BRD7/9 with DC50 values of 4.5 and 1.8 nM, respectively [1].
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Target
Epigenetic Reader Domain
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Related Pathways
Chromatin/Epigenetic
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CAS Number
2448358
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Purity
0.9895
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Molecular Formula
C22H28Cl2N4O3
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Molecular Weight
467.39
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SMILES
Cl.Cl.COc1cc(cc(OC)c1CN1CCNCC1)-c1cn(C)c(=O)c2cnccc12
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC