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BRD7-IN-1 free base - CAS 2305379-66-0

BRD7-IN-1 free base - CAS 2305379-66-0

MF-0020172-01

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Product Details

  • Bioactivity

    BRD7-IN-1 free base, a modified derivative of BI7273 (BRD7/9 inhibitor), interacts with a VHL ligand via a linker to form the PROTAC VZ185 (targeting BRD7/9 with DC50 values of 4.5 and 1.8 nM, respectively) [1].

  • Target

    Others, Epigenetic Reader Domain

  • Related Pathways

    Others, Chromatin/Epigenetic

  • CAS Number

    2305379-66-0

  • Molecular Formula

    C22H26N4O3

  • Molecular Weight

    394.47

  • SMILES

    O=C1C=2C=NC=CC2C(=CN1C)C=3C=C(OC)C(=C(OC)C3)CN4CCNCC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC