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Molfinity

Brepocitinib - CAS 1883299-62-4

Brepocitinib - CAS 1883299-62-4

SKU:MF-0013896-01

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  • Bioactivity

    Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor with IC50 values of 17 nM and 23 nM, respectively, and also inhibits JAK2 and JAK3 with IC50 values of 77 nM and 6.49 μM.

  • Target

    JAK, Tyrosine Kinases

  • Related Pathways

    JAK/STAT signaling, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Stem Cells, Angiogenesis

  • CAS Number

    1883233

  • Purity

    0.9982

  • Molecular Formula

    C18H21F2N7O

  • Molecular Weight

    389.4

  • SMILES

    C(=O)(N1C2CN(CC1CC2)C3=NC(NC=4C=NN(C)C4)=NC=C3)[C@H]5C(F)(F)C5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound