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Brigimadlin - CAS 2095116-40-6

Brigimadlin - CAS 2095116-40-6

SKU:MF-0095276-01

Regular price $192.16 USD
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  • Bioactivity

    Brigimadlin (BI 907828) is an orally active and highly potent E3 ubiquitin-protein ligase MDM2-p53 antagonist with antitumor activity.Brigimadlin can be used to study metastatic BTC, PDAC, lung adenocarcinoma, or bladder cancer.

  • Target

    MDM-2/p53, E1/E2/E3 Enzyme, Mdm2, p53

  • Related Pathways

    Ubiquitination, Apoptosis

  • CAS Number

    2095070

  • Purity

    0.9817

  • Molecular Formula

    C31H25Cl2FN4O3

  • Molecular Weight

    591.46

  • SMILES

    C(N1[C@@]2([C@H]([C@]3([C@@]1(CC=4N3N=C5C4C=CC(C(O)=O)=C5C)[H])[H])C6=C(F)C(Cl)=CC=C6)C=7C(NC2=O)=CC(Cl)=CC7)C8CC8

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound