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Molfinity

Brivanib - CAS 649735-46-6

Brivanib - CAS 649735-46-6

MF-0014136-01

$39.15 USD
$39.15 USD
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Product Details

  • Bioactivity

    Brivanib (BMS-540215) is an ATP-competitive inhibitor targeting VEGFR2 with an IC50 of 25 nM, exhibiting moderate potency against VEGFR-1 and FGFR-1, and over 240-fold selectivity against PDGFR-β. Phase 3.

  • Target

    Autophagy, EGFR, FGFR, VEGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, JAK/STAT signaling, Autophagy, Angiogenesis

  • CAS Number

    649683

  • Purity

    0.9887

  • Molecular Formula

    C19H19FN4O3

  • Molecular Weight

    370.38

  • SMILES

    C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound