Brivanib (alaninate) - CAS 649735-63-7

Brivanib Alaninate (BMS-582664) is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression.

FGFR, VEGFR, Autophagy

Angiogenesis, Autophagy, Tyrosine Kinase/Adaptors

649665

0.9966

C22H24FN5O4

441.46

C[C@H](COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C)OC(=O)[C@H](C)N

-20°C

Ice Packs

Small Compound