Bromodomain inhibitor-13 - CAS 1914047-59-8

Bromodomain Inhibitor-13 (Compound 1), an analog of PFI-3, is a bromodomain-containing protein (BCP) inhibitor. It specifically targets the bromodomains of SMARCA2, SMARCA4, and the first and second bromodomains of PB1 [PB1 (5) and PB1 (2) ], with dissociation constants (KD) of 37, 53, 30, and 190 nM, respectively.

Epigenetic Reader Domain

Chromatin/Epigenetic

1913980

C21H22N4O2

362.43

N(C1=C2C([C@@]3(N(/C=C/C(=O)C4=C(O)C=CC=C4)[C@](C2)(CC3)[H])[H])=NC=N1)C5CC5

-20°C

Ice Packs

Small Compound