Brompheniramine - CAS 86-22-6

Brompheniramine ((±) -Brompheniramine) is a potent, orally active alkylamine class antihistamine and a selective antagonist of the histamine H1 receptor (Kd = 6.06 nM) . It has applications in the research of allergic rhinitis and exhibits anticholinergic, antidepressant, and anesthetic properties. Brompheniramine blocks calcium channels, sodium channels, and hERG channels with IC50 values of 16.12 μM, 21.26 μM, and 0.90 μM, respectively [1] [2] [3] [4].

AChR, Histamine Receptor, Potassium Channel, Calcium Channel, Others, Sodium Channel

Metabolism, Others, Membrane transporter/Ion channel, Immunology/Inflammation, GPCR/G Protein, Neuroscience

58

C16H19BrN2

319.24

C(CCN(C)C)(C1=CC=C(Br)C=C1)C2=CC=CC=N2

-20°C

Ice Packs

Small Compound