BS-153 - CAS 1935692-54-8

BS-153 is a novel synthetic oxazolidinone drug that exhibits anti-inflammatory effects by blocking the activation of the NF-κB/PKCθ pathway. It can suppress the expression levels of iNOS, COX-2, and pro-inflammatory cytokines (TNF-α, IL-1β, and IL-6) in LPS-stimulated RAW264.7 cells.

NF-κB

NF-κB

1935630

C27H26ClF3N6O2

558.98

N#CC1=CC(=CC=C1N2CCC(N3CCOCC3)CC2)C(=O)NC=4C=NN(C5=CC=C(Cl)C=C5)C4C(F)(F)F

-20°C

Ice Packs

Small Compound