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Molfinity

BT2 - CAS 34576-94-8

BT2 - CAS 34576-94-8

MF-0014458-01

$31.68 USD
$31.68 USD
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Product Details

  • Bioactivity

    BT2, a BCKDC kinase (BDK) inhibitor, exhibits an IC50 of 3.19 μM and functions as a potent, selective Mcl-1 inhibitor with a Ki value of 59 μM. Its interaction with BDK induces helix movements in the N-terminal domain, leading to BDK's dissociation from the branched-chain α-ketoacid dehydrogenase complex (BCKDC) .

  • Target

    Bcl-2 Family

  • Related Pathways

    Apoptosis

  • CAS Number

    34474

  • Purity

    0.9986

  • Molecular Formula

    C9H4Cl2O2S

  • Molecular Weight

    247.1

  • SMILES

    OC(=O)c1sc2cc(Cl)ccc2c1Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound