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BTX161 - CAS 2052301-24-1
BTX161 - CAS 2052301-24-1
SKU:MF-0050084-01
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$1,050.35 USD
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$1,050.35 USD
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Product Details
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Bioactivity
BTX161 is a Thalidomide analogue. BTX161 is a potent CKIα degrader. In human AML cells, BTX161 mediates the CKIα degradation better than Lenalidomide as well as activates DNA damage response (DDR) and p53, and also stabilizes the p53 antagonist MDM2[1].
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Target
Others, Casein Kinase
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Related Pathways
Stem Cells, Metabolism, Others
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CAS Number
2052276
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Molecular Formula
C15H16N2O3
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Molecular Weight
272.3
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SMILES
Cc1cccc2C(=O)N(Cc12)[C@H]1CCCC(=O)NC1=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound