Bufarenogin - CAS 17008-65-0

Bufarenogin (3beta,12beta,14-Trihydroxy-11-oxo-5beta-bufa-20,22-dienolide) is a bufadienolide isolated from parotoid gland secretions of the Cuban endemic toad Peltophryne fustiger. Bufarenogin shows anti-tumor activity.

PI3K, Apoptosis, Bcl-2 Family, ERK, MEK

MAPK, PI3K/Akt/mTOR signaling, Apoptosis

16943

0.9877

C24H32O6

416.51

C[C@@]12[C@@](O)([C@]3([C@](C(=O)[C@H]1O)([C@]4(C)[C@](CC3)(C[C@@H](O)CC4)[H])[H])[H])CC[C@@H]2C=5C=CC(=O)OC5

-20°C

Ice Packs

Natural Product