Buformin hydrochloride - CAS 1190-53-0

Buformin hydrochloride (NSC-528218) is a potent AMPK activator, an oral antidiabetic drug of the biguanide class. Buformin delays the absorption of glucose from the gastrointestinal tract increases insulin sensitivity and glucose uptake into cells and inhibits synthesis of glucose by the liver. Biguanides may antagonize the action of glucagon, thus reducing fasting glucose levels.

AMPK

PI3K/Akt/mTOR signaling, Chromatin/Epigenetic

1137

0.9783

C6H16ClN5

193.68

Cl.CCCCNC(=N)NC(N)=N

-20°C

Ice Packs

Small Compound