Bufrolin - CAS 54867-56-0

Bufrolin, an analog of Cromoglycate (histamine release inhibitor) and a potent agonist of GPR35, enhances the interaction between β-arrestin-2 and both human GPR35a and rat GPR35. It stabilizes mast cells, exhibiting antiallergic properties, and inhibits anti-inflammatory responses triggered by internalization peptides. Furthermore, Bufrolin is researched for its anti-inflammatory properties in pharmaceutic applications associated with internalization peptides [1] [2] [3].

Histamine Receptor, GPCR, Others

Immunology/Inflammation, Others, GPCR/G Protein, Neuroscience, Endocrinology/Hormones

54811

C18H16N2O6

356.33

CCCCc1cc2c([nH]c(cc2=O)C(O)=O)c2c1[nH]c(cc2=O)C(O)=O

-20°C

Ice Packs

Small Compound