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Buparlisib Hydrochloride - CAS 1312445-63-8

Buparlisib Hydrochloride - CAS 1312445-63-8

SKU:MF-0013546-01

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  • Bioactivity

    Buparlisib Hydrochloride (BKM120 HCl) is a specific and orally bioavailable pan-class I PI3K inhibitor that competitively inhibits PI3K/AKT kinase at the nanomolar level and suppresses cancer cell growth, making it suitable for studying breast cancer, glioblastoma, and solid tumours.

  • Target

    Apoptosis, PI3K

  • Related Pathways

    PI3K/Akt/mTOR signaling, Apoptosis

  • CAS Number

    1312374

  • Purity

    0.9894

  • Molecular Formula

    C18H22ClF3N6O2

  • Molecular Weight

    446.85

  • SMILES

    Cl.FC(F)(F)C1=CC(=NC=C1C=2N=C(N=C(C2)N3CCOCC3)N4CCOCC4)N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound