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Buparlisib Hydrochloride - CAS 1312445-63-8
Buparlisib Hydrochloride - CAS 1312445-63-8
SKU:MF-0013546-01
Regular price
$36.91 USD
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$36.91 USD
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Product Details
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Bioactivity
Buparlisib Hydrochloride (BKM120 HCl) is a specific and orally bioavailable pan-class I PI3K inhibitor that competitively inhibits PI3K/AKT kinase at the nanomolar level and suppresses cancer cell growth, making it suitable for studying breast cancer, glioblastoma, and solid tumours.
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Target
Apoptosis, PI3K
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Related Pathways
PI3K/Akt/mTOR signaling, Apoptosis
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CAS Number
1312374
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Purity
0.9894
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Molecular Formula
C18H22ClF3N6O2
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Molecular Weight
446.85
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SMILES
Cl.FC(F)(F)C1=CC(=NC=C1C=2N=C(N=C(C2)N3CCOCC3)N4CCOCC4)N
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound