Bupranolol HCl - CAS 15148-80-8

Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with strong membrane stabilizing activity. Its potency is similar to propranolol. Bupranolol is quickly and completely absorbed from the gut. Over 90% undergo first-pass metabolism. Bupranolol has a plasma half life of about two to four hours, with levels never reaching 1 μg/l in therapeutic doses. The main metabolite is carboxybupranolol, 4-chloro-3-[3- (1,1-dimethylethylamino) -2-hydroxy-propyloxy]benzoic acid – that is, the methyl group at the benzene ring is oxidized to a carboxyl group –, of which 88% are eliminated renally within 24 hours.

Adrenergic Receptor, Others

Neuroscience, Others, GPCR/G Protein

15060

C14H23Cl2NO2

308.243

Cl.Cc1ccc(Cl)c(OCC(O)CNC(C)(C)C)c1

-20°C

Ice Packs

Small Compound