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Burixafor - CAS 1191448-17-5

Burixafor - CAS 1191448-17-5

SKU:MF-0111410-01

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  • Bioactivity

    Burixafor (also known as TG-0054) is an orally available inhibitor of the CXC chemokine receptor 4 (CXCR4) with receptor binding and hematopoietic stem cell mobilization activities. By binding to the CXCR4 chemokine receptor, Burixafor blocks the binding and subsequent activation of stromal cell-derived factor-1 (SDF-1 or CXCL12) with the CXCR4 receptor, potentially facilitating the mobilization of hematopoietic stem and progenitor cells from the bone marrow into the bloodstream. Note: Elemental analysis shows that this compound is a salt containing 3 HBr and 3 water molecules.

  • CAS Number

    1191426

  • Molecular Formula

    C27H51N8O3P

  • Molecular Weight

    566.72

  • SMILES

    N(C[C@@H]1CC[C@@H](CNCCCNC2CCCCC2)CC1)C=3N=C(C=C(N)N3)N4CCN(CCP(=O)(O)O)CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound