Butaprost - CAS 69685-22-9

Butaprost is a chemical compound that functions as a selective agonist for the prostaglandin E receptor (EP2) . It exhibits an EC50 of 33 nM and a Ki of 2.4 μM when interacting with the murine EP2 receptor. However, Butaprost demonstrates lower activity against murine EP1, EP3, and EP4 receptors. Furthermore, it effectively attenuates fibrosis by inhibiting the TGF-β/Smad2 signaling pathway [1] [2] [3].

TGF-beta/Smad, Others, Prostaglandin Receptor

Immunology/Inflammation, Others, Stem Cells, GPCR/G Protein

69654

C24H40O5

408.57

[C@@H](C/C=C/[C@@H]1[C@@H](CCCCCCC(OC)=O)C(=O)C[C@H]1O)(O)C2(CCC)CCC2

-20°C

Ice Packs

Small Compound