Butyrolactone Ia - CAS 942986-92-7

Butyrolactone Ia is an inhibitor of NO production, with an IC50 of 18 μM. It suppresses the mRNA expression of iNOS and inflammatory cytokine IL-1β induced by LPS. Additionally, Butyrolactone Ia regulates autophagy (autophagy) in HeLa cells and exhibits immunosuppressive activity.

NO Synthase, Interleukin, Autophagy

Immunology/Inflammation, Autophagy

942986-92-7

C23H22O7

410.417

C([C@]1(C(O)=O)C(=C(O)C(=O)O1)C2=CC=C(O)C=C2)C3=CC(CC=C(C)C)=C(O)C=C3

-20°C

Ice Packs

Natural Product