BV02 - CAS 292870-53-2

BV02 is an inhibitor of 14-3-3 protein-protein interactions and can be used in studies about the treatment of chronic myeloid leukemia. BV02 disrupts hematopoietic cells expressing the IM-resistant T315I mutation and the IM-sensitive wild-type Bcr-Abl.

Autophagy, Akt, Apoptosis, Caspase, PARP, Others, Antibacterial, Bcr-Abl

DNA Damage/DNA Repair, Apoptosis, Chromatin/Epigenetic, Autophagy, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling, Angiogenesis, Others, Proteases/Proteasome, Microbiology/Virology, Cytoskeletal Signaling

292815

0.9982

C20H15N3O5

377.35

Cc1c(N2C(=O)c3ccc(cc3C2=O)C(O)=O)c(=O)n(-c2ccccc2)n1C

-20°C

Ice Packs

Small Compound