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BVDU 5′-Triphosphate - CAS 77222-61-8
BVDU 5′-Triphosphate - CAS 77222-61-8
SKU:MF-0158113-01
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Product Details
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Bioactivity
BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase. It exhibits outstanding selectivity for varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1) owing to its phosphorylation by the virus-specific thymidine kinase.
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Target
DNA/RNA Synthesis, HSV
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Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Microbiology/Virology
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CAS Number
77153
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Molecular Formula
C11H16BrN2O14P3
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Molecular Weight
573.08
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SMILES
O=C1N([C@@H]2O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@@H](O)C2)C=C(/C=C/Br)C(=O)N1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound