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Molfinity

BVFP - CAS 357158-20-4

BVFP - CAS 357158-20-4

MF-0095435-01

$89.19 USD
$89.19 USD
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Product Details

  • Bioactivity

    BVFP is a PGRN-SORT1 inhibitor/SORT1 antagonist that binds to key residues 588-593 of PGRN, a multifunctional secreted glycoprotein, and SORT1, a neuronal receptor for PGRN.BVFP is able to block PGRN-SORT1 binding, restore extracellular levels of PGRN , inhibits SORT1-mediated rPGRN endocytosis, and has therapeutic potential for frontotemporal lobe dementia (FTLD-TDP) .

  • Target

    Neurotensin Receptor

  • Related Pathways

    GPCR/G Protein

  • CAS Number

    357134

  • Purity

    0.9874

  • Molecular Formula

    C13H8BrF3N2O

  • Molecular Weight

    345.12

  • SMILES

    O=C1N=C(C=CC=2C=CC=C(Br)C2)C=C(N1)C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound