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BVT-2733 hydrochloride - CAS 376641-65-5
BVT-2733 hydrochloride - CAS 376641-65-5
SKU:MF-0112524-01
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Product Details
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Bioactivity
BVT-2733 hydrochloride is a potent, selective, and orally active non-steroidal 11β-HSD1 inhibitor. It exhibits stronger inhibition on mouse 11β-HSD1 enzyme (IC50=96 nM) compared to the human 11β-HSD1 enzyme (IC50=3341 nM) . BVT-2733 hydrochloride shows potential for research in arthritis and obesity-related diseases.
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Target
Others, Dehydrogenase
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Related Pathways
Others, Metabolism
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CAS Number
376571
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Molecular Formula
C17H22Cl2N4O3S2
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Molecular Weight
465.42
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SMILES
Cl.O=C(N1CCN(C)CC1)CC=2N=C(SC2)NS(=O)(=O)C=3C=CC=C(Cl)C3C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound