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C-ABL-IN-4 - CAS 2626934-68-5
C-ABL-IN-4 - CAS 2626934-68-5
SKU:MF-0048907-01
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$1,383.80 USD
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Product Details
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Bioactivity
C-ABL-IN-4, a potent inhibitor of c-Abl, exhibits strong activity in inhibiting the Bcr-Abl (IC50 = 4.5 nM) kinase activity and proliferation (IC50 = 0.41-2.12 μM) of Bcr-Abl (T315I) cell lines.
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Target
Others, Bcr-Abl
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Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Others
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CAS Number
2626861
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Molecular Formula
C18H11ClF3N3O3
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Molecular Weight
409.75
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SMILES
O=C1N(C=C(C(NC2=CC=C(OC(Cl)(F)F)C=C2)=O)C=C1)C=3C=C(F)C=NC3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound