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Molfinity

C-Kit-IN-8 - CAS 2941024-89-9

C-Kit-IN-8 - CAS 2941024-89-9

MF-0142708-01

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Product Details

  • Bioactivity

    C-Kit-IN-8 (Compound 53) acts as an inhibitor of c-Kit kinase, hampering uKIT kinase activity with an IC50 greater than 1 μM. Additionally, it inhibits the proliferation of both wild-type and mutant GIST430 and BaF3 cancer cells, exhibiting an IC50 greater than 0.1 μM.

  • Target

    C-Kit

  • Related Pathways

    Tyrosine Kinase/Adaptors

  • CAS Number

    2940926

  • Molecular Formula

    C24H26FN5O4

  • Molecular Weight

    467.49

  • SMILES

    O=C(NC1=CC=C(C=C1)NC=2N=CN=C3C=C(OCCOC)C=C(F)C32)CCN4C(=O)CCC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound