C-Met/HDAC-IN-2 - CAS 2740495-53-6

C-Met/HDAC-IN-2 is a potent dual inhibitor of c-Met and HDAC, exhibiting IC50 values of 5.40 nM for c-Met and 18.49 nM for HDAC1, respectively. It demonstrates antiproliferative effects on various cancer cell lines, induces G2/M-phase arrest, and triggers apoptosis in HCT-116 cells, making it a promising candidate for anti-cancer resistance research.

Others, Apoptosis, c-Met/HGFR, HDAC

DNA Damage/DNA Repair, Chromatin/Epigenetic, Apoptosis, Others, Tyrosine Kinase/Adaptors

2740436

C34H33N5O7

623.66

O(C=1C2=C(C=C(OCCCCCCC(NO)=O)C(OC)=C2)N=CC1)C3=CC=C(NC(=O)C4=NN(C=CC4=O)C5=CC=CC=C5)C=C3

-20°C

Ice Packs

Small Compound