C-Met/HDAC-IN-3 - CAS 2439175-23-0

C-Met/HDAC-IN-3, a dual inhibitor targeting both c-Met and HDAC, exhibits potent inhibitory activity with IC50 values of 12.50 nM for c-Met and 26.97 nM for HDAC1. It induces apoptosis and causes cell cycle arrest in the G2/M phase.

Others, c-Met/HGFR, Apoptosis, HDAC

DNA Damage/DNA Repair, Apoptosis, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Others

2439152

C34H35FN4O7

630.66

O(C=1C2=C(C=C(OCCCCCCC(NO)=O)C(OC)=C2)N=CC1)C3=CC=C(NC(=O)C4C(=O)N(CC4)C5=CC=C(F)C=C5)C=C3

-20°C

Ice Packs

Small Compound