C-Met-IN-12 - CAS 2426675-70-7

C-Met-IN-12 is a selective, orally active type II c-Met kinase inhibitor (IC50: 10.6 nM) . c-Met-IN-12 is a high inhibitor of AXL, Mer and TYRO3 kinases (>80% inhibition at 1 μM) . c-Met-IN-12 can be used as a scaffold to further enhance kinase selectivity. c-Met-IN-12 exhibits anti-tumour activity.

Others, c-Met/HGFR

Others, Tyrosine Kinase/Adaptors

2426598

C34H29FN4O4

576.62

N(C1=C2C(N(C)C=C(C2=O)C3=CC=CC=C3)=CC=N1)C4=CC(F)=C(OC=5C6=C(C=C(OCC(C)(C)O)C=C6)N=CC5)C=C4

-20°C

Ice Packs

Small Compound