C16 Lactosylceramide (d18:1/16:0) - CAS 4201-62-1

C16 Lactosylceramide is an endogenous bioactive sphingolipid. It forms membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs), suggesting a role in cell signaling. Plasma levels of C16 lactosylceramide are elevated in insulin-resistant cattle. C16 Lactosylceramide is also upregulated in a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder.

Endogenous Metabolite, Others

Others, Metabolism

4201-62-1

C46H87NO13

862.18

O([C@@H]1[C@@H](CO)O[C@@H](OC[C@H](NC(CCCCCCCCCCCCCCC)=O)[C@@H](/C=C/CCCCCCCCCCCCC)O)[C@H](O)[C@H]1O)[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O

-20°C

Ice Packs

Small Compound