C18 Phytoceramide (t18:0/18:0) - CAS 34354-88-6

C18 Phytoceramide (t18:0/18:0) (Cer (t18:0/18:0) ) is a bioactive sphingolipid found in S. cerevisiae, wheat grains, and the stratum corneum layer of mammalian epidermis. It comprises a phytosphingosine backbone amine-linked to a C18 fatty acid chain. Cer (t18:0/18:0) regulates apoptosis, cell differentiation, smooth muscle cell proliferation, and inhibits the mitochondrial respiratory chain. It also suppresses the expression of allergic cytokines IL-4, TNF-α, and transcription factors c-Jun and NF-κB in histone-stimulated murine skin tissue. Formulations with cer (t18:0/18:0) are utilized in cosmetics as skin protectants, reducing water loss and preventing epidermal dehydration and irritation.

Others

Others

34260

C36H73NO4

583.983

CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)[C@H](O)CCCCCCCCCCCCCC

-20°C

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