(±) -C3001a - CAS 1374325-56-0

(±) -C3001a is the racemic mixture of C3001a (CAS: 2415154-29-7) . C3001a is a selective activator of the TREK channel within the two-pore-domain potassium channel (K2P) family. C3001a specifically binds to a cryptic site formed by P1 and TM4 in TREK-1, thereby promoting the selective regulation of TREK-1 activity. C3001a targets TREK channels in the peripheral nervous system, reducing the excitability of pain-sensing neurons.

Others, Potassium Channel

Membrane transporter/Ion channel, Others

1374269

0.9913

C21H20N2O3S

380.46

O=C(O)C1CCC(C(=O)NC2=CC=C(C=C2)C3=NC=4C=CC(=CC4S3)C)C1

-20°C

Ice Packs

Small Compound