C8 Galactosylceramide (d18:1/8:0) - CAS 41613-16-5

C8 Galactosylceramide is a synthetic C8 short-chain derivative of known membrane microdomain-forming sphingolipids. It increases the amount delivered and toxicity of doxorubicin in cancerous but not non-cancerous cells when incorporated into the nanoliposomal membrane of nanoliposomal-doxorubicin. C8 Galactosylceramide induces proliferation and cytokine production by splenocytes in vitro at concentrations ranging from 100-1,000 ng/ml but has no effect on natural killer T cell production in vivo. It also activates NF-κB production in C6 glioma cells when used at a concentration of 10 μM.

Others

Others

41592

C32H61NO8

587.83

O(C[C@H](NC(CCCCCCC)=O)[C@@H](/C=C/CCCCCCCCCCCCC)O)[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O

-20°C

Ice Packs

Small Compound