CA224 - CAS 883561-04-4

CA224 (Compound 1), an orally active and selective Cdk4–cyclin D1 inhibitor, demonstrates an IC50 of 6.2 μM. It induces cell apoptosis and exhibits antitumor activity [1].

Apoptosis, Others, CDK

Apoptosis, Others, Cell Cycle/Checkpoint

883561-04-4

C24H22N2O

354.44

C(CN(C(=O)C1=CC=C(C=C1)C2=CC=CC=C2)C)C=3C=4C(NC3)=CC=CC4

-20°C

Ice Packs

Small Compound