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Cabozantinib hydrochloride - CAS 1817759-42-4

Cabozantinib hydrochloride - CAS 1817759-42-4

MF-0048155-01

$37.66 USD
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Product Details

  • Bioactivity

    Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM) .

  • Target

    C-Kit, FLT, Apoptosis, VEGFR, c-Met/HGFR, ROR, TAM Receptor

  • Related Pathways

    Tyrosine Kinase/Adaptors, Apoptosis, Metabolism, Angiogenesis

  • CAS Number

    1817713

  • Purity

    0.9997

  • Molecular Formula

    C28H25ClFN3O5

  • Molecular Weight

    537.96

  • SMILES

    Cl.COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound