CAD204520 - CAS 2682205-20-3

CAD204520 functions as an inhibitor of SERCA (IC50 = 0.34 μM), specifically targeting mutations in the wild-type NOTCH1 protein associated with T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL) .

Calcium Channel, Gamma-secretase

Proteases/Proteasome, Stem Cells, Neuroscience, Membrane transporter/Ion channel, Metabolism

2682182

C23H32F3N3O2

439.51

FC(F)(F)OC=1C=CC2=C(C1)NC(=C2CCC)C3N(CCN4CCOCC4)CCCC3

-20°C

Ice Packs

Small Compound