CAFESTOL - CAS 469-83-0

CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX) -2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production by suppressing the NF-kB activation pathway.

ERK, FAK, Autophagy, COX, NF-κB, Apoptosis, DNA/RNA Synthesis, PGE Synthase

Angiogenesis, Tyrosine Kinase/Adaptors, Apoptosis, Autophagy, Cytoskeletal Signaling, Neuroscience, Cell Cycle/Checkpoint, DNA Damage/DNA Repair, MAPK, Immunology/Inflammation, NF-κB

386

0.9984

C20H28O3

316.43

[H][C@@]12C[C@]3(C[C@]1(O)CO)CC[C@]1([H])c4ccoc4CC[C@@]1(C)[C@]3([H])CC2

-20°C

Ice Packs

Natural Product